Product Name: Mannitol
Synonyms: D-Mannitol, mannite
CAS No.: 69-65-8
INS No.: 421
H.S. Code: 29054300
Molecular Formula: C6H14O6 (182.2)
Weight: 182.2
Description:
Mannitol is a sugar alcohol; that is, it is derived from a sugar by reduction, with a molecular weight of 182.17 g/mol, and a density of 1.52 g/mL. Other sugar alcohols include xylitol and sorbitol. Mannitol and sorbitol are isomers, the only difference being the orientation of the hydroxyl group on carbon 2. Aqueous solutions of mannitol are mildly acidic.
Specification: BP2018, USP36, EP8.0, FCC V
| Items |
Specification |
| Appearance |
White or almost white, crystalline powder or free-flowing granules |
| Identification |
Conforms |
| Solubility |
Soluble in water, slightly soluble in ethanol |
| Melting Range |
164° ～ 169° |
| Acidity |
≤0.30mL |
| Colour of Solution |
Clear and Colorless |
| Opitical Rotation |
+137° ～ 145° |
| Chloride |
≤0.007% |
| Sulfate |
≤0.01% |
| Reducing Sugars |
≤0.20% |
| Loss on Drying |
≤0.3% |
| Arsenic |
≤1ppm |
| Assay |
96.0 ～ 101.5% |
| Total Viable Aerobic |
100pcs/g |
| Escherichia Coli |
Negative |
| Salmonella |
Negative |
| Bacteria Endotoxins |
Conforms |
Allergenics: The product contains none of the ingredients of the list of allergenics of the EC.
Packing and Transportation: Adopting the package of 25kg/bag with net kraft bag and PE inner. The transportation shall be in accordance with the requirement of general chemicals.
Usage:
Food Application – Mannitol is used as a sweetener for people with diabetes, and in chewing gums. It also has a low glycemic index, making it a low carb food. It does not pick up water from the air until the humidity level is 98%, which makes mannitol very useful as a coating for hard candies, dried fruits, and chewing gums, and it is often included as an ingredient in candies and gum. The pleasant taste and mouthfeel of mannitol also makes it a popular excipient for chewable tablets.
Good Sweetness: only 0.55-0.65 if sugar is 1;
Low Calorie Value: about 1.6kcal/g, 40% of sugar;
Not easy to absorb moisture;
Very Stable: no physical or chemical reaction with medicine ingredients;
Slow calcium phosphate precipitation - help the body to absorb calcium.
Pharmaceutical Application - Mannitol is used to increase urine production (diuretic), to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). This medication is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.
Shelf Life: 24 months
Storage: Store in a cool, dry, ventilated environment.
